He was born in Lisbon and in 1548 joined the Society of Jesus (Jesuits). In 1563, he came to Japan to spread his gospel, and in the following year arrived at Kyoto, meeting Ashikaga Yoshiteru who was then Shogun. In 1569, he met Oda Nobunaga.
His writings include the History of Japan by Luis Frois.
See also: Francis Xavier