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U.S. Highway 22

United States Highway 22, an east-west route, is one of the original United States highways of 1926. It originally ran from Cambridge, Ohio in the west to Elizabeth, New Jersey in the east; today, it runs from Cincinnati, Ohio to Newark, New Jersey near the Newark Airport.

Highway 22 is also referred to as William Penn Highway throughout most of Pennsylvania.

Table of contents
1 Termini
2 States Traversed
3 Related US Routes
4 Sources


As of 2004, the highway's eastern terminus is in Elizabeth, New Jersey at an intersection with US 1 and US 9. Its western terminus is in Cincinnati, Ohio at an intersection with US 27, US 42, US 127, and US 52.

States Traversed

The highway passes through the following states:

Related US Routes