1962 saw the Isley Brothers release "Twist and Shout", a moderate hit of The Topnotes song later made famous by The Beatles. In 1964, a then-unknown guitarist named Jimmy James began playing in their backing band, making his recording debut on "Testify". James eventually began his own career under the name Jimi Hendrix. After joining with Motown, the Isley Brothers recording "This Old Heart of Mine (Is Weak for You)", a hit in England in 1967.
After a spell living in England, the Isley Brothers returned to the US and released "It's Your Thing", a popular record nationwide. After adding a few more family members and friends to the group, the Isley Brothers began moving towards rock and roll, covering "Lay Lady Lay" (Bob Dylan), "Spill the Wine" (Eric Burdon & War) and "Love the One You're with" (Stephen Stills). In the early 1970s, the Isley Brothers released several more hits and began moving towards disco. Their career was mostly over, in spite of several moderate R&B hits throughout the later 70s and 1980s. The group was later inducted into the Rock and Roll Hall of Fame, and was also inducted into the Vocal Group Hall of Fame in 2003.