Kemp won two American Football League Western Division championships with the Los Angeles - San Diego Chargers before being picked up by the Buffalo Bills. He led Buffalo to three straight Eastern Division titles and two American Football League championsips, in 1964 and 1965, throwing to Hall of Fame receivers Elbert Dubenion and Ernie Warlick. Kemp was the first 3,000 yard passer in the American Football League (1960, 14-game schedule)and the league's Most Valuable Player in 1965. He had the most career passes attempted, most completions and most yards gained passing in the history of the American Football League. Jack Kemp was an American Football League All-Star six consecutive years and for seven of the league's ten years, and the only AFL quarterback to be a starter all ten years. Kemp co-founded the American Football League Players Association and was elected its president five times. He was one of only twenty players who were in the American Football League for its entire ten-year existence, and is a member of the American Football League Hall of Fame.
Kemp represented the Buffalo, New York region in the United States House of Representatives from 1971 to 1989. He subsequently served as the Secretary of Housing and Urban Development from 1989 to 1993 under President George H. W. Bush. In 1996 he was the Republican Vice Presidential candidate.