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In Greek mythology, Astydameia was the Queen of Iolcus and wife of Acastus.

Acastus purifed Peleus of the murder of King Eurytion of Phthia Then, Peleus lost a wrestling match in the funeral games of Pelias, Acastus' father, to Atalanta. Astydameia, Acastus' wife, fell in love with Peleus but he scorned her. Bitter, she sent a messenger to Antigone, Pelias' wife and daughter of Eurytion, to tell her that Peleus was to marry Acastus' daughter, Steropes; Antigone hanged herself.

Astydameia then told Acastus that Peleus had tried to rape her. Acastus took Peleus on a hunting trip and hid his sword, then abandoned him right before a group of centaurs attacked. Chiron, the wise centaur, returned Peleus' sword and Peleus managed to escape. He pillaged Iolcus and dismembered Astydameia, then marched his army between the pieces. Acastus and Astydamia were dead, and the kingdom fell to Jason's son, Thessalus.

Alternative: Astydamia, Astydamea