The first USS South Carolina was originally L'Indien, a frigate built in Amsterdam for American agents in France during the American Revolutionary War.
The second USS South Carolina was a schooner built for the Revenue Cutter Service.
The third USS South Carolina was a coastal patrol vessel.
The fourth USS South Carolina was a screw steamer that saw action in the American Civil War.
The fifth USS South Carolina (BB-26) was the lead ship of her class of battleship.
The sixth USS South Carolina (CGN-37) was a California-class nuclear-powered guided missile cruiser.