The plot is taken from the Menaechmi, and to a smaller extent from the Amphitruo, of Plautus. It concerns two sets of twins, Antipholus of Ephesus and Antipholus of Syracuse, and their respective servants, Dromio of Ephesus and Dromio of Syracuse. When they all end up in the same place at the same time, there are several cases of mistaken identity which give rise to comedy.
William Warner's translation of the Menaechmi was entered in the Stationers' Register on June 10, 1594. A performance of The Comedy of Errors by "a company of base and common fellows" is recorded in the Gesta Grayorum as taking place in Gray's Inn hall on December 28, 1594.
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