An enlarged 10MB two-platter ST-506
The ST506 was interfaced to the microcomputer using an S-100 bus card which could control up to four drives. Unlike modern systems where the data is sent to the drive and the drive itself is supposed to deal with it, in the ST506 the entire system was controlled by the controller and the disks were "dumb", connected to the controller with two cables. The 34-pin control cable would control the mechanical motions of the drive with pins such as "head select 2" which it would use to position the head, and then data could be read or written serially using only two pins of the 20 pin data cable. This led to slow potential performance due to the limited bandwidth of the data cable, although this was not an issue at the time.
A number of other companies quickly introduced drives using the same connectors and signals, creating an ST506-based hard drive standard. By the time the IBM PC was being introduced in the 1980s it was universal. IBM wisely chose to use it, building an adaptor card for their expansion system in the PC.
Almost all drives in the 1980s were ST506-based. However the complexity of the controller and cabling led to newer solutions like SCSI, and later, ATA (IDE). In most cases SCSI drives were in fact ST506 drives with a SCSI to ST506 adaptor on the bottom of the drive. This sort of solution continues to this day.