Neot seems to have begun his adult life as a soldier, later renouncing this for life in a monastery. He served as sacristan at Glastonbury Abbey but later lived in Cornwall, at first alone, then with a growing group of other monks near Bodmin Moor. He was remembered (and given the status of a saint) because of his good work in caring for the poor. The Cornish village of St Neot (village) is named after him.
His bones were preserved as a holy relic but were later taken by monks to the medieval priory at St Neots on the River Great Ouse near Bedford. They returned with their prize, pursued according to some versions by angry Cornishmen.
There is a large mosaic picture of the saint in the Market Square in St Neots