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Penzance is a port in Cornwall, England, facing west onto the English Channel. It is the westernmost town in England, and was incorporated in 1615. It presently has a population of about 20,000 people.

The name Penzance is derived from the Cornish per san, meaning "holy headland", it is the principal town on the Land's End peninsula.

It was the birthplace of chemist Sir Humphry Davy.

Places of interest in Penzance include Penlee House - an art gallery and museum, notable for its collection of paintings by members of the Newlyn School.