Orange Park is the home of the Yerkes Regional Primate Research Center, one of ten regional centers for primate research. The Orange Park center, established in 1930 by Yale University, was the first laboratory in the United States for the study of non-human primates. It is now a part of Emory University.
The name reflects the hope of its founders for a fruit-growing industry, but their crops were destroyed in the Great Freeze of 1894-95. Despite recovery elsewhere, the crops never came back to Orange Park.
According to the United States Census Bureau, the town has a total area of 14.4 km² (5.6 mi²). 10.1 km² (3.9 mi²) of it is land and 4.3 km² (1.6 mi²) of it is water. The total area is 29.73% water.
As of the census of 2000, there are 9,081 people, 3,429 households, and 2,362 families residing in the town. The population density is 899.0/km² (2,331.1/mi²). There are 3,648 housing units at an average density of 361.2/km² (936.4/mi²). The racial makeup of the town is 82.95% White, 10.96% African American, 0.52% Native American, 2.31% Asian, 0.04% Pacific Islander, 1.44% from other races, and 1.77% from two or more races. 4.60% of the population are Hispanic or Latino of any race.
There are 3,429 households out of which 28.7% have children under the age of 18 living with them, 53.9% are married couples living together, 11.9% have a female householder with no husband present, and 31.1% are non-families. 25.4% of all households are made up of individuals and 9.0% have someone living alone who is 65 years of age or older. The average household size is 2.45 and the average family size is 2.92.
In the town the population is spread out with 21.0% under the age of 18, 7.9% from 18 to 24, 24.8% from 25 to 44, 25.3% from 45 to 64, and 21.0% who are 65 years of age or older. The median age is 43 years. For every 100 females there are 90.3 males. For every 100 females age 18 and over, there are 87.7 males.
The median income for a household in the town is $47,631, and the median income for a family is $58,093. Males have a median income of $36,590 versus $26,846 for females. The per capita income for the town is $24,087. 7.5% of the population and 4.6% of families are below the poverty line. Out of the total people living in poverty, 10.8% are under the age of 18 and 17.1% are 65 or older.