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Menthol is a compound obtained from peppermint oil or other mint oils or made synthetically. Menthol has local anesthetic and counterirritant qualities. It is contained in nonprescription products for short-term relief of minor sore throat and minor mouth or throat irritation. Menthol is also contained in combination products used for relief of muscle aches, sprains, and similar conditions.

There are currently no reported nutrient or herb interactions involving menthol. People using combination products that include menthol are advised to review the other ingredients for possible herb and/or nutrient interactions. Menthol is considered an antidote for many homeopathic remedies and should be avoided by people taking them.