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Ironweed is a 1987 film which tells the story of an alcoholic, wandering man and woman during the Great Depression. It stars Jack Nicholson, Meryl Streep, Carroll Baker, Michael O'Keefe, Diane Venora, Fred Gwynne, Tom Waits and Nathan Lane.

The movie was adapted by William Kennedy from his novel. It was directed by Hector Babenco.

It was nominated for Academy Awards for Best Actor in a Leading Role (Jack Nicholson) and Best Actress in a Leading Role (Meryl Streep).

Ironweed is any plant species of the genus Vernonia.