Fibrinolytic
The fibrinolytics are a class of
pharmaceuticals that act as thrombolytics by activating plasminogen to form plasmin. Activated plasmin degrades
fibrin and so breaks up
thrombi. The fibrinolytics are used in thrombolytic therapy of
myocardial infarct and pulmonary embolisation.
The most important fibrinolytics are :
- streptokinase
- alteplase
- reteplase
- tenecteplase