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Duccio di Buoninsegna (c.1260-c.1319) was probably the most influential Sienese artist of his time. Duccio is considered to have had a major influence on the formation of the International Gothic style. He is considered to have influenced Simone Martini and the brothers Ambrogio and Pietro Lorenzetti among others.

His works include the Rucellai Madonna (1285) for Santa Maria Novella (now in the Uffizi) and the Maestà (1308-11) for Siena's cathedral.