Vreeland Came to the United States of America at the outbreak of World War I. In 1924, she married Thomas Reed Vreeland, who died in 1967 and had two sons. She became a naturalized American citizen and lived in Albany, New York, from 1924-1928. Vreeland lived in London until 1937, when her husband's job brought them back to New York.
Her fashion career began in 1937 as columnist for Harper's Bazaar. Joined Vogue in 1962, where she was editor-in-chief until 1971. She became consultant to the Costume Institute of the Metropolitan Museum of Art in New York in 1971.