Commentary is known for its passionate support for Israel, for opposition to any Palestinian state, and for favoring American unilaterist foreign policy. It has advocated regime change by force in Iraq and other countries considered hostile to the interests of Israel and the United States, including Iran, Syria, Lebanon, Jordan, Saudi Arabia, Egypt and Libya. The case for placing the oil fields of Saudi Arabia under permanent American military occupation has also been advocated by Commentary.
The founders of neooconservatism, Irving Kristol and Norman Podhoretz have both served as editors of Commentary Magazine.