After many years working as secretary to various MPs - latterly her husband - she rose to prominence when she loudly confronted her husband's oppponent Martin Bell on Knutsford Heath during the election campaign. After the election the Hamiltons appeared togther on Have I Got News For You, an appearance that established her as a chat-show personality. Her own television show was only a short-lived novelty, but she continued to seek the limelight, appearing on a "reality television" programme, I'm a Celebrity, Get Me Out of Here in 2002.
Along with her husband, Christine Hamilton was arrested in May 2001 by police investigating an alleged rape. Their accuser was later imprisoned for attempting to pervert the course of justice.