He was born in Hugo, Oklahoma and was raised in Texas. Moyers began his journalism career at age 16 as a cub reporter at the Marshall News Messenger in Marshall, Texas. He and his wife, Judith Davidson Moyers, have three grown children.
During the Kennedy Administration, Moyers was appointed as Deputy Director of the Peace Corps (1961–63). When Lyndon Baines Johnson took office after the Kennedy assassination, Moyers became special Assistant to President Johnson and also served as Johnson's press secretary from 1965 to 1967.
Best known for his work as a journalist, Moyers served as publisher for the Long Island, New York daily Newsday from 1967-1970. In 1986, Moyers and his wife Judith Davidson formed Public Affairs Television. One of their first productions was the popular PBS series Joseph Campbell and the Power of Myth (1988).
Moyers currently hosts the show NOW with Bill Moyers on PBS.