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Anheuser-Busch ("A-B"), the world's largest brewing company, is based in Saint Louis, Missouri. Anheuser-Busch's best known beers include brands such as Budweiser (not to be confused with the Czech beer of the same name), and the Busch and Michelob families. A-B also produces a number of smaller-volume and specialty beers, nonalcoholic brews, malt liquors, and flavored malt beverages.

The company is known in the United States for its huge advertising presence, including a sports marketing division which creates advertising material for the Super Bowl and many other sporting events. Famous Busch television campaigns have included the "Gimme a light" spots, frogs and lizards saying 'bud-wei-ser', the annual Bud Bowl, the "Waazzzup" series, and others.

A-B owns Busch Gardens, Sea World, and several other amusement parks and resorts, as well as production, transportation and packaging operations related to its beer business.

The St. Louis Cardinals baseball team was owned by A-B from the mid 1950s until it was sold to a group of private investors in March 1996. Busch Stadium still bears the name of the brewery, although there are plans to demolish and replace the stadium by 2006.