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Afrotheria are a clade of mammals that has been proposed based on DNA analysis. Afrotheria are believed to have originated in Africa at a time when the continent was isolated from other continents. Their only externally visible common characteristic is the movable snout. The clades contained in Afrotheria are:

Some Afrotherian clades are analogous to clades of mammals outside of Afrotheria; for example, Sirenia to whales, tenrecs to Insectivora, Paenungulata to other ungulates, aardvarks to anteaters.