See also: 1599 in science, other events of 1600, 1601 in science, and the list of years in science.
December 31 - British East India Company is founded.
Tadoussac, France's first trading post on the mainland of New France (now Canada), is established
William Gilbert publishes De Magnete which describes the Earth's magnetic field and is the beginning of modern geomagnetism.
Ludolph van Ceulen computed the first 35 decimals of &pi at about this time.
William Gilbert coins the word electricity.
Simon Stevin invents a carriage propelled by sails.
John Ogilby, cartographer